abstract：:The superior olivary complex (SOC) is part of the auditory brainstem of the vertebrate brain. Residing ventrally in the rhombencephalon, it receives sensory signals from both cochleae through multisynaptic pathways. Neurons of the SOC are also a target of bilateral descending projections. Ascending and descending effe...

journal_title：Microscopy research and technique

authors： Illing RB,Kraus KS,Michler SA

更新日期：2000-11-15 00:00:00

abstract：:The principal functions of the gastrointestinal tract mucosa include nutrient absorption, protein and fluid secretion, and the regulated symbiosis with intraluminal contents. Research in epithelial biology has benefited significantly from the use of cultured monolayer preparations, which closely replicate the structur...

journal_title：Microscopy research and technique

authors： Gilbert RJ,Hoffman M,Capitano A,So PT

更新日期：2000-10-15 00:00:00

abstract：:A cognitive task can often be subdivided into several subprocesses, which follow a specific temporal order. Here, we report an event-related functional magnetic resonance imaging (fMRI) experiment on memory search, in which the temporal onset of search in primary memory was varied relative to retrieval from secondary ...

journal_title：Microscopy research and technique

authors： Pollmann S,Zysset S,Wiggins CJ,Von Cramon DY

更新日期：2000-10-01 00:00:00

abstract：:Isoform diversity in striated muscle is largely controlled at the level of transcription. In this review we will concentrate on studies concerning transcriptional regulation of the alkali myosin light chain 1F/3F gene. Uncoupled activity of the MLC1F and 3F promoters, together with complex patterns of transcription in...

journal_title：Microscopy research and technique

authors： Kelly RG,Buckingham ME

更新日期：2000-09-15 00:00:00

abstract：:The photoreceptor population in Xenopus consists of a green-sensitive rod (lambda(max) = 523 nm), a blue-sensitive rod (lambda(max) = 445 nm) and three classes of cone. The largest cone is red-sensitive (lambda(max) = 611 nm). The intermediate cone is presumed to be blue-sensitive based on physiological criteria, wher...

journal_title：Microscopy research and technique

authors： Witkovsky P

更新日期：2000-09-01 00:00:00

abstract：:The apolipoprotein E (apoE) epsilon4 allele increases risk of Alzheimer's disease (AD), perhaps by accelerating plaque formation, or by impairing neuron repair. Considerable evidence supports both mechanisms. AD patients with epsilon4 have more and earlier amyloid deposits than do patients without epsilon4. The same i...

journal_title：Microscopy research and technique

authors： Baum L,Chen L,Ng HK,Pang CP

更新日期：2000-08-15 00:00:00

abstract：:Tumor necrosis factor (TNF) exists in two bioactive forms, the membrane integrated form and the proteolytically derived soluble cytokine. Both forms of TNF are involved in a variety of different physiological and pathophysiological situations. Here we analyzed different human and mouse TNF-specific reagents for their ...

journal_title：Microscopy research and technique

authors： Gerspach J,Götz A,Zimmermann G,Kolle C,Böttinger H,Grell M

更新日期：2000-08-01 00:00:00

abstract：:The discovery of new song types in Hawaiian Drosophila species has raised a question of alternative sound production and sound perception mechanisms in Drosophila. For example D. disjuncta males, which produce song with a carrier frequency of 5,000-6,000 Hz, do not vibrate their wings but only tremble them in a very s...

journal_title：Microscopy research and technique

authors： Hoikkala A,Moro S

更新日期：2000-07-15 00:00:00

abstract：:The cellular prion protein PrP(c) is a neurolemmal glycoprotein essential for the development of the transmissible spongiform encephalopathies. In these neurodegenerative diseases, host PrP(c) is converted to infectious protease-resistant isoforms PrP(res) or prions. Prions provoque predictable and distinctive pattern...

journal_title：Microscopy research and technique

authors： Haeberlé AM,Ribaut-Barassin C,Bombarde G,Mariani J,Hunsmann G,Grassi J,Bailly Y

更新日期：2000-07-01 00:00:00

abstract：:The ultrastructural characteristics of peptidergic peripheral contacts in the snail, Helix pomatia, were investigated, with special attention to the innervation of the heart, buccal mass, and salivary gland by Mytilus inhibitory peptide-immunoreactive neurons. Following the application of correlative light- and electr...

journal_title：Microscopy research and technique

authors： Elekes K

更新日期：2000-06-15 00:00:00

abstract：:In animal oocytes, the centrosome exists as an acentriolar aggregate of centrosomal material that is regulated in a dynamic manner throughout the process of meiotic maturation. Recently, it has been demonstrated that in female meiotic systems spindle assembly is likely regulated by chromosomal and microtubule/microtub...

journal_title：Microscopy research and technique

authors： Carabatsos MJ,Combelles CM,Messinger SM,Albertini DF

更新日期：2000-06-01 00:00:00

abstract：:This review article focuses on the ontogeny and the regulatory mechanisms involved in the modulation of the intracellular events governing the assembly and delivery of lipoproteins in human gut. The human fetal intestine organizes villi covered with well-differentiated enterocytes during the end of the first trimester...

journal_title：Microscopy research and technique

authors： Levy E,Ménard D

更新日期：2000-05-15 00:00:00

abstract：:The through focus exit wave reconstruction technique uses a series of high resolution electron microscopy images to reconstruct the complex electron wavefunction at the exit plane of the specimen. The feasibility of the through focus exit wave reconstruction method and its most important limitations are discussed. It ...

journal_title：Microscopy research and technique

authors： Zandbergen HW,Van Dyck D

更新日期：2000-05-01 00:00:00

abstract：:The small GTPase Rho, which regulates cell shape, is thought to contribute to cytokinesis. Recently, Citron was characterized as a Rho target. This large protein contains a Ser/Thr kinase domain related to that of ROCK, another Rho effector. Both endogenous Citron and recombinant Citron localize to the cleavage furrow...

journal_title：Microscopy research and technique

authors： Madaule P,Furuyashiki T,Eda M,Bito H,Ishizaki T,Narumiya S

更新日期：2000-04-15 00:00:00

abstract：:During late anaphase and telophase, animal cells develop a bundle of antiparallel, interdigitating microtubules between the two daughter nuclei. Recent data indicate that this structure, called the central spindle, plays an essential role during cytokinesis. Studies in Drosophila and on vertebrate cells strongly sugge...

journal_title：Microscopy research and technique

authors： Gatti M,Giansanti MG,Bonaccorsi S

更新日期：2000-04-15 00:00:00

abstract：:Many aspects of the organization of the electromotor synapse of electric fish resemble the nerve-muscle junction. In particular, the postsynaptic membrane in both systems share most of their proteins. As a remarquable source of cholinergic synapses, the Torpedo electrocyte model has served to identify the most importa...

journal_title：Microscopy research and technique

authors： Cartaud J,Cartaud A,Kordeli E,Ludosky MA,Marchand S,Stetzkowski-Marden F

更新日期：2000-04-01 00:00:00

abstract：:Directed growth cone movement is crucial for the correct wiring of the nervous system. This movement is governed by the concerted actions of cell surface receptors, signaling proteins, cytoskeleton-associated molecules, and molecular motors. In order to investigate the molecular basis of growth cone motility, we appli...

journal_title：Microscopy research and technique

authors： Buchstaller A,Jay DG

更新日期：2000-01-15 00:00:00

abstract：:Neurons begin to polarize when one of the neurites becomes the axon. Hippocampal neurons in cell culture have a sharp transition between their unpolarized and polarized stage revealed by the rapid growth of the future axon. Recent progress shows that both a cytoplasmic membrane flow and actin dynamics govern axon form...

journal_title：Microscopy research and technique

authors： Bradke F,Dotti CG

更新日期：2000-01-01 00:00:00

abstract：:Studies in insect gustation have a long history in general physiology, particularly with work on fly labellar and tarsal sensilla and in the general field of insect-plant interactions, where work on immature Lepidoptera and chrysomelid beetles has been prominent. Much more emphasis has been placed on the physiological...

journal_title：Microscopy research and technique

authors： Mitchell BK,Itagaki H,Rivet MP

更新日期：1999-12-15 00:00:00

abstract：:This manuscript reviews gap junctions' roles in control of intestinal motility. Gap junctions (GJs) of small intestine (SmIn) are found between circular muscle (CM) cells, between interstitial cells of Cajal (ICC) of deep muscular plexus (DMP) and between them and adjacent outer circular muscle (OCM). GJs between long...

journal_title：Microscopy research and technique

authors： Daniel EE,Wang YF

更新日期：1999-12-01 00:00:00

abstract：:Multifunctional involvement of actin microfilaments during viral infection has been documented in many studies. The molecular mechanism underlying this important host-virus interaction, however, remains poorly understood. We have investigated the role of actin microfilaments in the life cycle of human parainfluenza vi...

journal_title：Microscopy research and technique

authors： De BP,Banerjee AK

更新日期：1999-10-15 00:00:00

abstract：:Actin, though highly conserved, exhibits a myriad of diverse functions, most of which ultimately depend on its intrinsic ability to rapidly assemble and disassemble filamentous structures. Many organisms synthesize multiple actin isoforms even within the same cell. Tissue-specific expression patterns and tight develop...

journal_title：Microscopy research and technique

authors： Schoenenberger CA,Steinmetz MO,Stoffler D,Mandinova A,Aebi U

更新日期：1999-10-01 00:00:00

abstract：:A re-examination and modification of the very old oblique illumination technique has resulted in a method for contrast enhancement in microscopes, diffracted-light contrast (DLC), which provides high-contrast, high-resolution images of unstained biological material. The technique, which utilizes the diffracted light f...

journal_title：Microscopy research and technique

authors： Piekos WB

更新日期：1999-08-15 00:00:00

abstract：:The catecholaminergic cell groups in the human brain, denominated from A1 to A17, display some striking anatomical differences with those described in the rodent. These differences are essentially observed in the extent of the dopaminergic neurons and especially their axonal fields in the telencephalon. Immunocytochem...

journal_title：Microscopy research and technique

authors： Verney C

更新日期：1999-07-01 00:00:00

abstract：:The neurotrophins are a diverse family of peptides which activate specific tyrosine kinase-linked receptors. Over the past five decades, since the pioneering work of Levi-Montalcini and colleagues, the critical role that neurotrophins play in shaping the developing nervous system has become increasingly established. T...

journal_title：Microscopy research and technique

authors： Behrens MM,Strasser U,Lobner D,Dugan LL

更新日期：1999-05-15 00:00:00

abstract：:A new and improved technique for microvascular corrosion casting was developed and verified by examination of corrosion casts of 90 bovine limbs. The described technique renders a complete filling of the vasculature of the claw even in regions that hitherto proved to be difficult regarding completeness of filling such...

journal_title：Microscopy research and technique

authors： Hirschberg RM,Mülling CK,Bragulla H

更新日期：1999-05-01 00:00:00

abstract：:Cell-free extracts of Xenopus eggs were used to investigate how differing lamin sub-types are incorporated into a lamina and how lamina composition influences DNA replication. Purified recombinant human lamin A (HlaminA) was inoculated into egg extracts, which support in vitro nuclear assembly. The route of incorporat...

journal_title：Microscopy research and technique

authors： Dyer JA,Lane BE,Hutchison CJ

更新日期：1999-04-01 00:00:00

abstract：:Atomic force microscopy has been used to study self-assembled structures of two alpha-hemolysin mutants. For a mutant (alphaHL-H5) that was locked into the prepore state on fluid phase egg-PC membranes, we visualized, for the first time, heptameric prepores and showed that the 7-fold axis in the prepore lies perpendic...

journal_title：Microscopy research and technique

authors： Malghani MS,Fang Y,Cheley S,Bayley H,Yang J

更新日期：1999-03-01 00:00:00

abstract：:During the emergence of multicellular organisms, molecular mechanisms evolved to allow maintenance of anatomical integrity and self-recognition. We propose that carbohydrates from proteoglycans, as the most peripheral cell surface, and matrix molecules might have provided these key adhesion and recognition functions. ...

journal_title：Microscopy research and technique

authors： Misevic GN

更新日期：1999-02-15 00:00:00

abstract：:One of the lessons learned from studying the nervous systems of phylogenetically distant species is that many features are conserved. Indeed, aminergic neurons in invertebrate and vertebrate systems share a multitude of common characteristics. In this review, the varied roles of serotonin, octopamine, dopamine, and hi...

journal_title：Microscopy research and technique

authors： Beltz BS

更新日期：1999-01-15 00:00:00

abstract：:The anatomical substrate for coordinated release from the dispersed gonadotropin-releasing hormone (GnRH) neuronal population remains obscure. There is physiological evidence that the GnRH hormone itself has a role in tonic inhibition or modulation of GnRH function. This has led to the hypothesis that there is an ultr...

journal_title：Microscopy research and technique

authors： Witkin JW

更新日期：1999-01-01 00:00:00

abstract：:The mammary adenocarcinoma cell line MTLn3 is chemotactic towards epidermal growth factor (EGF), and this induced motility is thought to promote breast cancer invasion and metastasis. Stimulation of MTLn3 cells with EGF results in the extension of a flat, thin structure filled with filamentous actin and termed a lamel...

journal_title：Microscopy research and technique

authors： Bailly M,Condeelis JS,Segall JE

更新日期：1998-12-01 00:00:00

abstract：:The avian pancreas has three or four lobes and develops from a dorsal and two ventral buds. The cells that will contribute to formation of the dorsal bud are at first located in the mid-dorsal endoderm, those of the ventral buds in the floor of the foregut. The determination of endoderm to form dorsal and ventral bud ...

journal_title：Microscopy research and technique

authors： Rawdon BB

更新日期：1998-11-15 00:00:00

abstract：:E-cadherin and its associated cytoplasmic proteins alpha-, beta-, and gamma-catenin, play a crucial role in epithelial cell-cell adhesion and in the maintenance of tissue architecture. Perturbation in the expression or function of any of these molecules results in loss of intercellular adhesion, with possible conseque...

journal_title：Microscopy research and technique

authors： El-Bahrawy MA,Pignatelli M

更新日期：1998-11-01 00:00:00

abstract：:Cartilage morphogenesis is a prerequisite for skeletal development and maintenance. The morphogenesis of cartilage determines the shape of bones, and joints including articular cartilage, ligaments, and tendon. This article reviews the recent advances in cartilage-derived morphogenetic proteins (CDMPs) and related bon...

journal_title：Microscopy research and technique

authors： Reddi AH

更新日期：1998-10-15 00:00:00

abstract：:Twelve substrains of inbred senescence-accelerated mice (SAM) have been developed, among which the SAMP8 and SAMP10 strains show a significant age-related deterioration in learning and memory for passive and active avoidance tasks. These strains have, respectively, a low and high incidence of systemic senile amyloidos...

journal_title：Microscopy research and technique

authors： Kawamata T,Akiguchi I,Maeda K,Tanaka C,Higuchi K,Hosokawa M,Takeda T

更新日期：1998-10-01 00:00:00

abstract：:The autonomic neuromuscular junction at a varicosity in the vas deferens is defined by the localization of the vesicle-associated protein syntaxin in high concentrations in the axolemma and a high density of P2x1 receptors in a cluster beneath the varicosity. Calcium fluxes have been observed in all individual varicos...

journal_title：Microscopy research and technique

authors： Bennett MR,Cheung A,Brain KL

更新日期：1998-09-15 00:00:00

abstract：:In order to fulfill its many functions as the selective interface between maternal and fetal circulations it is imperative that the human placenta remains intact and in good operational order. That damage of some sort occurs during its short but extremely active life seems inevitable given the dynamic environment in w...

journal_title：Microscopy research and technique

authors： Watson AL,Burton GJ

更新日期：1998-09-01 00:00:00

abstract：:This paper summarizes the essential features of the various facilities dedicated to in situ irradiation effects research around the world at the present time, mentions some essential techniques that are involved in this type of research, and describes very briefly some examples of studies employing these facilities an...

journal_title：Microscopy research and technique

authors： Allen CW,Ryan EA

更新日期：1998-08-15 00:00:00

abstract：:The anterior adhesive areas of a monocotylid monogenean, Merizocotyle australensis (Merizocotylinae), were investigated. They comprise 6 ventral apertures in 2 groups of 3 arranged at the anterolateral margins of the head. These regions are also well supplied with groups of cilia. Each aperture is 13.8 to 15.8 microm ...

journal_title：Microscopy research and technique

authors： Cribb BW,Whittington ID,Chisholm LA

更新日期：1998-08-01 00:00:00